Additionally, SENP1 negativity try associated with the TNBC (P = 0

Additionally, SENP1 negativity try associated with the TNBC (P = 0 Additionally, MEL-18 exhaustion prevents the brand new deSUMOylation pastime out of SENP1 by the raising the BMI-1/RING1B E3 ubiquitin ligase cutting-edge–mediated ubiquitin-proteasomal degradation out of SENP1 We also confirmed the positive correlation of SENP1 protein expression with MEL-18 expression in 223 human breast tumors […]